The 12 Best Cat Pheromone Spray 2021

If you are a cat owner, perhaps you have had instances when your kitty misbehaves or is extremely anxious.

Of course, that is not a good thing and you would want a quick fix to help your cat settle down and stop misbehaving.

Cat pheromones are a good example of a one-step fix that will calm your cat down in case they work and it is important to understand this crucial fact before purchasing.

That said, you need to be on the lookout for the best cat pheromone spray that will put them off places they are not supposed to be and relax them at the same time.

Cat Pheromone Spray: Comparison List

Here’s our brief and concise comparison table that brings together all the badass sprays you might be looking for. Keep scrolling for our detailed review of each one of them.

1Comfort Zone Feliway Diffuser Refills for Cats5 x 2.1 x 7.8 inches6.4 ounces
2Feliway Plug-In Diffuser Refill3.5 x 2 x 6 inches7.2 ounces
3Feliway MultiCat Calming Diffuser Refill1.8 x 1.8 x 3.2 inches6.4 ounces
4ThunderEase Multicat Calming Pheromone Diffuser Refill5.3 ounces
5Feliway Classic Calming Diffuser Refill1.8 x 1.8 x 3.2 inches0.64 ounces
6ThunderEase Cat Calming Pheromone Diffuser Refill5.3 ounces
7Pet Diesel Premium Pet Deodorizer8 x 1.75 x 1.75 inches8 Ounces
8Comfort Zone Multicat Calming Diffuser Refill5.63 x 3.69 x 3.56 inches14.02 Ounces
9Bach Flower Remedies Essences Rescue Remedy Spray4.23 x 2.03 x 1.12 inches16 ounces
10FELIWAY Spray Classic Spray1.57 x 1.57 x 4.72 inches2.65 Ounces
11Pet Organics No-Stress Spray for Cats2.75 x 2.75 x 9.75 inches19.2 ounces
12Only Natural Pet Just Relax Botanical Cat Calming Spray 6.75 x 1.75 x 1.75 inches3.2 Ounces

1. Comfort Zone Feliway Diffuser Refills

Should you be wondering how to deal with your cat’s anxiety due to changes like new furniture in the house or remodeling, scratch your head no more!The Comfort Zone diffuser is here with all the answers. The pheromones emitted from the diffuser signal to your pet that the environment is safe and friendly.

This Comfort Zone product has been clinically proven to help in reducing vertical scratching and urine marking. These are signs that your cat is uncomfortable or stressed out.

Key Features

The product is unscented and drug-free. Therefore, it is useable with minimal risks of allergic reactions from drugs or unpleasant strong scents that may cause sneezing.

Simply plug the diffuser unit into an outlet in the room where your pet has scratched or urine marked then observe to notice the changes. Remember to refill after every 30 days and replace the diffuser after 12 months.


  • The diffuser refill is easy to use
  • This product is clinically proven to be effective
  • It is drug-free and unscented
  • This Comfort Zone product has no side effects


  • The diffuser gets too hot and starts to melt away

2. Feliway Plug-In Diffuser Refill

The Feliway product is designed to mimic facial pheromones that are naturally comforting to cats. As a result, cat stress-related behaviors are reduced or completely stopped.

The product is convenient since you get three bottles in one pack that will last long. The bottles are refillable after 30 days.

Key Features

This product from Feliway is easy to use. Once you have unpacked it, you plug the diffuser into an outlet in the area where your cat spends most time then it will emit the pheromones to calm your pet.

You can use Feliway product on your pet because it is clinically proven as effective and drug-free. Moreover, no side effects have been reported even after long term use.


  • This Feliway product is simple to use
  • It is unscented and drug-free
  • No side effects have been reported by long term users
  • The product is clinically proven to be effective


  • It does not work with some cats

3. Feliway Multi Cat Diffuser Refill

Feliway Multicat product helps calm your cats, thus enabling them to socialize and live harmoniously. Get yourself a bottle and observe the hostile environment change for the better.

The product has been clinically proven as effective in dealing with multi-cat tension. Behaviors like biting, hissing, fighting are controlled once you introduce Feliway into your home.

Key Features

Veterinarians recommend the use of this Feliway product to deal with urine marking by cats and vertical scratching. It is said to take effect within seven days.

Feliway Multicat works by mimicking a mother cat’s pheromones that naturally calm. These pheromones produced send a message to the cat’s brain resulting in peace and relaxed interactions.


  • This Feliway diffuser is easy to use
  • It is unscented
  • This Feliway product is clinically approved
  • Results are visible within seven days when using the product


  • They run out pretty fast

4. Thunder Ease Multicat Calming Pheromone Diffuser Refill

This product from ThunderEase helps your cats to get along by reducing how frequently they fight. It works by mimicking nursing pheromones that have a calming and socializing effect.

Veterinarians recommend it to assist in dealing with unwanted cat behaviors like spraying of urine and scratching. You place it in the room where your cat has marked, then observe for behavioral changes.

Key Features

The product is clinically proven to be 90% effective in dealing with stress-related behaviors in cats. Veterinarians also recommend it for use.

ThunderEase Multicat is drug-free and simple to use. You screw the refill bottle on to the diffuser head and plug into an outlet ensuring the bottle goes below.


  • This calming pheromone is simple to use
  • Its effectiveness is clinically proven
  • This ThunderEase product has no drugs in it
  • Long term use of the product causes no side effects


  • The contents in the bottle run out faster than expected

5. Feliway Classic Diffuser Refill

Feliway Classic diffuser is clinically proven to be effective. It works efficiently in reducing stress-related behaviors affecting your cat.

Veterinarians recommend the use of Feliway Classic when dealing with reactions from your cat due to environmental changes. It produces pheromones that calm and makes your cat more interactive.

Key Features

Feliway Classic has no drugs in it and it is unscented. Long term users have reported having no side effects when using the product on their cats or on themselves.

This Feliway product is said to produce results within seven days. Unfortunately, the bottles last for 20 days yet the product label shows it should last for 30 days.


  • Results are visible within seven days
  • The product is clinically proven to work
  • Feliway Classic is drug-free and unscented
  • It has no side effects


  • You have to purchase a diffuser head separately

6. ThunderEase Cat Calming Pheromone Diffuser Refill

ThunderEase diffuser helps in reducing stress-related behaviors in your cat. The pheromones emitted from the diffuser result in a calmer and better-behaved cat.

The diffuser is easy to plug in and use with 90% proven effectiveness. You can start to see results within a week of using the ThunderEase diffuser.

Key Features

To help curb pet anxiety, destructive scratching and urine spraying, veterinarians recommend the use of this ThunderEase product. It is clinically tested and certified to be safe on cats.

There are no reported side effects with the use of ThunderEase diffuser even after long periods. Furthermore, it has neither drugs nor chemicals and it is odorless.


  • This product is odorless and drug-free
  • It is easy to use
  • Clinical tests prove its effectiveness
  • There are no reported side effects


  • At nine out of ten on effectiveness, it does not work on many cats

7. Pet Diesel Premium Pet Deodorizer

This product from Pet Diesel contains essential therapeutic-grade oils and herbal oils. These help in dealing with bacterial and fungal infections in pets that may lead to bad odor.

The pet deodorizer is said to be non-toxic but it has tea tree oil as an ingredient. Tea tree oil is known to be toxic to cats, thus some customers do not use the product.

Key Features

The pet deodorizer, which can also be used as an air freshener, has four scents to choose from. Moreover, it is 100% biodegradable.

When your cat is anxious and emotionally stressed, this pet deodorizer helps in calming and relaxing them. The eucalyptus and peppermint essential oils play an important role in relieving stress-related behaviors.


  • You can use this pet product as a deodorizer and air freshener
  • It can be sprayed directly on the pet
  • This product has four scents to choose from
  • Premium pet deodorizer assists in the treatment of infections


  • This pet deodorizer has tea tree oil which is known to be toxic to cats

8. Comfort Zone MultiCat Calming Diffuser Refill

Comfort Zone diffuser has twice the amount of pheromones as compared to the other diffusers. This means it is more effective and efficient.

This product from Comfort Zone works to reduce stress-related situations in your cat, like vertical scratching, urine spraying or marking. Once plugged in, it calms your cat, making it feel safe and more interactive.

Key Features

The diffuser has been designed to shut off whenever it gets too hot for safety purposes. This reduces the chances of melted and burnt plastic diffusers in your house.

The Comfort Zone diffuser is tested and certified as safe on your cat. It has neither chemicals nor drugs and is unscented.


  • This product has two times more pheromones
  • The product has been tested and certified to be safe
  • It is drug-free
  • There are no side effects associated with the use of this product


  • The bottle contents get depleted very fast

9. Bach Flower Rescue Remedy Spray

This spray has five Bach Flower essences that work to calm your pet down. Each essence has its particular function to ensure that the stressful situations are dealt with well.

It is easily portable since the bottle can fit in your bag or pocket. The spray nozzle is brought to the mount then two sprays are applied on to the tongue, quick and easy.

Key Features

The spray can be used by both humans and pets, but the pet version has no alcohol ingredient. It has no known side effect even with long term use.

According to some customers, it has a pleasant taste while others dislike it. As for the cats, it is tricky to ascertain how they find the taste.


  • The spray has no side effects
  • It works effectively
  • Using this spray is simple
  • The spray bottle can easily fit into your bag or pocket


  • Some customers find its taste to be terrible

Also read: 15 Best Cat Scratching Post – Reviews

10. Feliway Spray Classic Spray

The spray has pheromones that assist in comforting your cat during travels. You have to spray into your cat’s carrier and wait for 15 minutes before you can put the pet in.

This Feliway spray can help reduce behaviors like scratching and urine spraying. While avoiding not spraying into the air, use eight pumps on the affected surface areas daily until the behavior stops.

Key Features

This seems like a good spray but the precautions are a bit discouraging, having to wait for 15 minutes before your cat can access the sprayed carrier is not easy. It is better to get a spray with no or fewer precautions.

Each application of this spray can last between four and five hours and you can reapply when necessary. This spray leaves no stains on the surfaces you spray but the applications may have to be frequent for effectiveness.


  • The spray has a comforting effect
  • This spray can help reduce scratching and urine spraying
  • When used on surfaces, no staining occurs
  • Feliway Spray is easy to use


  • You have to wait for 15 minutes before your cat can access the sprayed area

11. Pet Organics No-Stress Spray

The spray can be used to calm your cat in situations where they get anxious, for example, when traveling for long distances. You spray inside the carrier and not on the cat.

This spray’s fragrance, which mimics cat pheromones, is mild and pleasant. The pheromones work well to relax your nervous cat to enable you to have a more peaceful time.

Key Features

The spray is natural with no drugs or chemicals in it. However, some customers find the mild fragrance to be unpleasant and irritating to their nostrils.

To use the spray, press the nozzle and directing it on to the surface that your cat scratches or where they shower with urine when they are nervous. It should not be mistaken for a tranquilizer due to its calming effects.


  • The spray has a mild sweet fragrance
  • Using the spray is easy
  • This spray is effective in calming your cat
  • It has no drugs or chemicals in it


  • Some customers react to the mild fragrance

12. Only Natural Pet Pheromone Spray

The spray helps to calm your cat whenever it experiences stressful situations like long journeys. The natural essential oils affect the nerves of your cat, enabling them to relax and even fall asleep.

You can use this spray on all cat breeds of any age. It works effectively within a short time.

Key Features

This spray is easy to use and it should be sprayed on surfaces or in the cat’s carrier not on the cat, it does not stain surfaces. However, the manufacturer failed to indicate how often it should be used.

The spray is natural with no chemicals or drugs in it. There are no reported side effects with its use.


  • You can use the spray on cats of any age
  • This spray is 100% natural
  • It is unscented
  • Using the spray is easy


  • How often the spray should be used is not indicated

Pheromone Spray for Cat: Buying Guide

The best cat pheromone should be able to deliver particular results. This means that you have to consider a few things such as:

Do you want a Calming or Aggressive Pheromone?

There are two kinds of pheromones that can safely be used in the home: Aggressive and calming pheromones.

The aggressive kind is one that you can spray on your kitty to keep other cats away or just keep them away from wherever you do not want them to be.

A calming pheromone is what your cat will release when they are happy or comfortable. This kind of spray will help your kitty feel more relaxed by making them believe that they are in a safe area which another cat has vouched for.

Simply put, if you want your cat to stay away from an area, use the aggressive spray, and if you want them to be comfortable in an area, spray it with a pheromone spray.

Time Away

Cats are not good travelers and most of the time, any changes to their routine can cause trauma. As such, you may want to leave them behind.

During such times, you can seize the opportunity and use your spray pheromone to calm them down and prevent them from lashing out at your belongings.

Alternatively, you can bring your cat along and use a pheromone spray to keep them relaxed. Packing a deterrent travel spray will also go a long way in keeping your guest destination safe from your cat’s tantrums.

Target Area

As you go for a cat pheromone spray, you probably have a place in mind where you want your cat to stay away from or stay put.

Theoretically, you can spray an entire room but the results will not be as effective because you would have sprayed in the air.

One thing you need to keep in mind that pheromone sprays are not aerosol and therefore do not have a long range.

If you want long range coverage, you will be better off using a pheromone diffuser but with a pheromone spray, you would have to spray the particular area you are targeting for best results.


Catnip is a stimulant which when included in a pheromone spray can increase its effectiveness. However, you need to be extra careful that your kitty not to develop a tolerance for the stimulant.

While at it, it is also important to keep in mind that cats respond differently to catnip. While some may actually calm down, others will be hyperactive.

If your aim is to just help your cat fell less anxious and less stressed, then catnip is a good choice. However, if you are looking to calm down your easily excited cat, you may want to rethink introducing stimulant into their system.

The Water Bottle Approach

If you spend more time with your cat, you can use deterrent sprays to instantly fix undesirable behavior. The pheromone spray will not only put them off, but they will also not like the act of being sprayed.

Spraying them while in the act is probably the best way to arrest bad behavior in your cat.

Urine Marking

You may realize that your cat marks with urine and this is a huge indication that they are struggling with some form of anxiety.

Typically, you can stop your kitty from doing that by assigning them a spot where they will feel safe and secure.

In case they have developed a urine marking habit, you will find that an aggressive pheromone spray comes in handy because it will stop reoccurrence.

If there is something in your desired spot that causes anxiety in your cat, using a pheromone spray will help solve the problem.

Frequently Asked Questions (FAQ)

Here are some common questions on this topic that can be of help.

Does Pheromone spray really work for cats?

Pheromones are colorless and odorless chemical signals for specific species. As such, if a product is designed for dogs, it will not work on cats.

Calming cat pheromones come in different formats such as wet wipes, sprays, collars, and diffusers. To answer your question, yes, pheromones will work if they were specifically created for cats.

Can I get calming medicine for my cat?

Yes, you can. There are calming cat treats and cat food in the market. You can get your cat on a calming food diet if you want long-term effects and calming treats for short-term effect.

What else aside from pheromones can I give my cat to calm them down?

Chamomile works wonders. Just as human beings drink chamomile tea to relax, cats can also do the same because chamomile’s anti-anxiety properties have the same effect on them.

The only thing is that you will not give your cat tea but chamomile’s dried leaves.

Is pheromone spray safe for my cat?

Yes, most pheromone sprays are generally safe for cats. However, be careful not to spray into any open wounds or your kitty’s eyes.

While doing so is not harmful to your cat, it may cause irritation.

Best Overall Choice

Our best cat pheromone spray is Comfort Zone Feliway Diffuser Refill since it contains all that you would need for your stressed cat. Besides, it is safe to use for both the pet and the owner. We highly recommend this high-quality product for its effectiveness.

Final Thoughts

Animals release pheromones which are chemicals meant to affect animals of the same species in their area. When it comes to cats, they release different pheromones to signal different things.

Cats will either release an aggressive or calming pheromone depending on what they feel about their area.

With a spray pheromone, you can be able to control your cat’s behavior in terms of whether you want to embrace or reject something or someplace. With this guide, you now know how to go about it.

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